In vitro activities of SCH27899 alone and in combination with 17 other antimicrobial agents.

نویسندگان

  • P C Fuchs
  • A L Barry
  • S D Brown
چکیده

SCH27899, an everninomicin antibiotic, was tested for its in vitro activity against 718 bacterial isolates representing 27 species. The Enterobacteriaceae and nonenteric gram-negative bacilli were resistant to > or = 8.0 microg/ml, but all others were inhibited by < or = 1.0 microg/ml. When tested in combination with 17 other antimicrobial agents against 110 strains, SCH27899 demonstrated no significant antagonism or synergy. Consequently, combination therapy is not contraindicated.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 43 12  شماره 

صفحات  -

تاریخ انتشار 1999